Its construction, following plans of Diego de Siloé, took place from the middle of the XVI century until the end of the XVIII century, date when the paralization of the work was ordered by royal command.

It combines perfectly diverse architectural styles: Gothic in the ground floor, Rennaisace in its elevation, and Baroque in the main facade and decoration of its roof. Among the works of arts, special atention deserve the Choir Stalls, by Pedro de Mena.

The north tower rises to 84 meters in height, being the second highest cathedral in Andalusia, after the Giralda in Seville. The south tower is unfinished. This condition gives the Cathedral the nickname of 'La Manquita' (the one-armed).